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Succinate dehydrogenase (SDH) deficient renal carcinoma - a morphologically distinct entity:

A clinicopathologic series of 36 tumors from 27 patients.

 

Anthony J Gill, Ondrej Hes, Thomas Papathomas, Monica Šedivcová, Puay Hoon Tan, Abbas Agaimy, Per Arne Andresen, Andrew Kedziora, Adele Clarkson, Christopher W Toon, Loretta Sioson, Nicole Watson, Angela Chou, Julie Paik, Roderick J Clifton-Bligh, Bruce G Robinson, Diana E Benn, Kirsten Hills, Fiona Maclean, Nicolasine D Niemeijier, Ljiljana Vlatkovic, Arndt Hartmann, Eleonora P M Corssmit, Geert J L H van Leenders, Christopher Przybycin, Jesse K McKenney, Cristina Magi-Galluzi, Asli Yilmaz, Darryl Yu, Katherine D Nicoll, Jim L Yong, Mathilde Sibony, Evgeny Yakirevich, Stewart Fleming, Chung W Chow, Markku Miettinen, Michal Michal and Kiril Trpkov.

 

American Journal of Surgical Pathology. December 2014 - Volume 38 - p 1588-1602

 

Case 1: 35yo male. 75mm right kidney tumor. Stage 2(T2AN0).

Case 2: 76yo female. 25mm left kidney tumor. Stage 1(T1AN0).

Case 3: 32yo female. 68mm right kidney tumour. Stage 1(T1BN0).

Case 4a: Male. 34yo. 50mm right kidney. Stage 1(T1BN0).

 

Case 4b: Male 35yo. 75mm left kidney. Stage 2(T2AN0).

Case 4c: Male 35yo. 47mm left kidney. Stage 1(T1BN0).

Case 4d: Male 35yo. 40mm left kidney. Stage 1(T1AN0).

Case 5a: Male 45yo. 50mm left kidney. Stage 1(T1BN0).

Case 5b: Male 45yo. 41mm left kidney. Stage 1(T1BN0).

Case 5c: Male 45yo. 7mm right kidney. Stage 1(T1AN0).

Case 6: 43yo female. 8mm left kidney tumor. Stage 1(T1AN0).

Case 7: 31yo female. 35mm right kidney tumor. Stage 1(T1AN0).

Case 8: 16yo male. 45mm right kidney tumor. Stage 1(T1BN0).

Case 9: 46yo male. 85mm right kidney tumor.

Case 10: 30yo female. 90mm right kidney tumor. Stage 2(T2AN0).

Case 10: Vertebral metastasis 30 years after first presentation.

Case 11a: Male. 14yo. Left kidney tumor.

Case 11b: Male. 18yo. Right kidney tumor.

Case 11c: Male. 18yo. Right kidney tumor.

Case 12: 44yo female. High Fuhrman nuclear grade tumor.

Case 13: 57yo male. 60mm right kidney tumor. Stage p3(T3aN0).

Case 14: 54yo male. 28mm right kidney tumor. Stage 1(T1aN0).

Case 15: 27yo male. Bilateral disease. Biopsy of metastasis.

Case 16: 21yo female. 22mm right kidney tumor. Stage 1(T1ANO).

 

Case 17: 28yo male. 29mm left kidney tumor. Stage 1(T1A).

Case 18: 22yo male. 100mm left kidney tumor. Stage 4.

Case 19: 58yo female. 78mm left kidney tumor. Stage 2(T2AN0).

Case 20: 22yo female. 65mm right kidney tumor. Stage 1(T1BN0).

Case 21a: 25yo male. 90mm left kidney tumor. Stage 1(T1AN0).

Case 21b: 25yo male. 28mm left kidney tumor. Stage 1(T1AN0).

Case 22: 23yo male. 25mm right kidney tumor. Stage 1(T1AN0).

Case 23: 36yo male. 130mm left kidney tumor. Stage 2(T2BN0).

 

Case 24: 40yo male with stage 4 disease.

Case 25: 35yo male.

Case 26: 44yo male with stage 4 disease.

Case 27: 59yo female. 70mm right kidney tumor. Stage 2(T2AN0).

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